Research Group

James M Fick, Ph.D.

Post Doctoral Researcher

Tissue and cell mechanics

Personal information

  • Phone: +358 044 912 7971
  • Address: Department of Applied Physics, University of Eastern Finland, POB 1627, 70211 Kuopio, Finland. Room 343
  • Email: james.fick[at]uef.fi (please fix the address before mailing!)

  • Date of birth: 31 July 1980

  • Present position: Postdoctoral Researcher, University of Eastern Finland, Kuopio, FI

  • Current research interests:
    • Biomechanics/Tissue mechanics (e.g. cartilage, ligaments, tendons, meniscus, bone)
    • Cell mechanics
      • Orthopaedics/Osteoarthritis
      • Mechanotransduction/Mechanosensation
    • Biomaterials/Implantology/Replacement materials

  • Previous research experience:
    • 2009 – 2012, Technical Officer - Executive, Poultry Industry Association of New Zealand (PIANZ) Auckland, NZ
    • 2003 - 2004, Graduate Research Assistant, University at Buffalo, Buffalo, NY
    • 2000 - 2005, Laboratory Technician, Allegheny Ludlum, Lockport, NY
    • 2002, Lab Assistant, Stueben Foods, Elma, NY

  • Education:
    • Ph.D in Chemical & Materials Engineering, Research Topic: Cartilage Research, Thesis Topic: Response of Articular Cartilage to Compression: An Investigation in Relation to Matrix Health, New Zealand, Auckland, University of Auckland 2005-2011 (part time)
    • MSc in Biomaterials, Thesis Topic: Customized Contact Lens Treatments for in-the-Eye Medication: Drug Delivery Through Contact Lenses Biomaterials Program, State University of New York at Buffalo, Buffalo, New York, USA
    • BSc, Major: Engineering Materials, State University of Buffalo at New York, Buffalo, New York, USA

  • Language proficiency:
    • English, native language

  • Skills:
    • Biomechanical testing, microscopy techniques (FTIR, PLM, DD), chondrocyte mechanics

  • Teaching Experience
    • 2008 – Summer Lecturer, Faculty of Engineering, University of Auckland

  • Acknowledged technical contributions:
    • Meyer AE, Baier RE, Chen H, Chowhan M (2006) Differential tissue-on-tissue lubrication by ophthalmic formulations, Journal of Biomaterials Research Part B: Applied Biomaterials, 82b, 74-88.
    • Meyer AE, Baier RE, Chen H, Chowhan M (2006) Tissue-on-Tissue Testing of Dry Eye Formulations for Reduction of Bioadhesion, The Journal of Adhesion, 82, 607-627.

  • Acknowledged peer review contributions:
    • Mäkelä JT, Huttu MR, Korhonen RK (2012): Structure-function relationships in osteoarthritic human hip joint articular cartilage, Osteoarthritis Cartilage, http://dx.doi.org/10.1016/j.joca.2012.07.016
    • Väänänen, S P, Isaksson, H, Waarsing, E, Zadpoor, A A, Jurvelin, J S, Weinans, H (2012).:Estimation of 3D rotation of femur in 2D hip radiographs. Journal of Biomechanics. http://dx.doi.org/10.1016/j.jbiomech.2012.06.007

  • Provisional Patent:
    • Co-Inventor of U.S. Provisional Patent: s/n 60/869, 929 titled of “Photocatalytic and Protective Self-Cleaning Contact Lenses”.

Publications:

(full papers, conference proceedings)
  1. Fick JM, P Ronkainen A, Madden R, Sawatsky A, Tiitu V, Herzog W and Korhonen RK. Early in situ changes in chondrocyte biomechanical responses due to a partial meniscectomy in the lateral compartment of the mature rabbit knee joint. J Biomech. 2016 Dec 8;49(16):4057-4064. doi: 10.1016/j.jbiomech.2016.10.039. Epub

  2. Ronkainen AP, Fick JM, Herzog W and Korhonen RK. Site-specific cell-tissue interactions in rabbit knee joint articular cartilage. J Biomech. 2016 Sep 6;49(13):2882-2890. doi: 10.1016/j.jbiomech.2016.06.033. Epub

  3. Fick JM, Ronkainen A, Herzog W and Korhonen RK. Site-dependent biomechanical responses of chondrocytes in the rabbit knee joint. J Biomech. 2015 Nov 26;48(15):4010-9. doi: 10.1016/j.jbiomech.2015.09.049. Epub

  4. Korhonen RK, Tanska P, Kaartinen SM, Fick JM and Mononen ME. New Concept to Restore Normal Cell Responses in Osteoarthritic Knee Joint Cartilage. Exerc Sport Sci Rev. 2015 Jul;43(3):143-52. doi: 10.1249/JES.0000000000000051.

  5. Arokoski ME, Tiitu V, Jurvelin JS, Korhonen RK and Fick JM. Topographical investigation of changes in depth-wise proteoglycan distribution in rabbit femoral articular cartilage at 4 weeks after transection of the anterior cruciate ligament. J Orthop Res. 2015 Sep;33(9):1278-86. doi: 10.1002/jor.22906. Epub 2015 May 21.

  6. Florea C, Malo MK, Rautiainen J, Makela JT, Fick JM, Nieminen MT, Jurvelin JS, Davidescu A and Korhonen RK. Alterations in subchondral bone plate, trabecular bone and articular cartilage properties of rabbit femoral condyles at 4 weeks after anterior cruciate ligament transection. Osteoarthritis Cartilage. 2015 Mar;23(3):414-22. doi: 10.1016/j.joca.2014.11.023.

  7. Fick JM, Huttu MR, Lammi MJ and Korhonen RK. In vitro glycation of articular cartilage alters the biomechanical response of chondrocytes in a depth-dependent manner. Osteoarthritis Cartilage. 2014 Oct;22(10):1410-8. doi:

  8. Fick JM. How the structural integrity of the matrix can influence the microstructural response of articular cartilage to compression. Connect Tissue Res. 2013;54(2):83-93. doi: 10.3109/03008207.2012.746321. Epub

  9. Fick JM and Espino DM. Articular cartilage surface failure: an investigation of the rupture rate and morphology in relation to tissue health and hydration. Proc Inst Mech Eng H. 2012 May;226(5):389-96. doi: 10.1177/0954411912439824.

  10. Fick JM and Espino DM. Articular cartilage surface rupture during compression: investigating the effects of tissue hydration in relation to matrix health. J Mech Behav Biomed Mater. 2011 Oct;4(7):1311-7. doi:

  11. Fick JM, Thambyah A and Broom ND. Articular cartilage compression: how microstructural response influences pore pressure in relation to matrix health. Connect Tissue Res. 2010 Apr;51(2):132-49. doi: 10.3109/03008200903125229.

  1. Fick JM, Thambyah A, Broom ND (2008): ASME Summer Biomechanics Conference, Marco Island, Florida, USA, “The Microstructural Response of Articular Cartilage at Peak Internal Pore Pressure: A Comparison Between Normal and Degenerate Matrices”.

  2. Fick JM, Thambyah A, Broom ND (2007): Microscopy Conference, Auckland New Zealand: “An Insight Into the Microanatomical Failure of Healthy and Degenerate Cartilage Via Differential Interference Contrast Microscopy”.

  3. Fick JM, Thambyah A, Broom ND (2007): Australasian Biomechanics Conference, Auckland, New Zealand, “Cartilage Extrusion: A Novel Method to Investigate Tissue Failure as a Function of Degenerative Weakening”.

  4. Fick JM, Thambyah A, Broom ND (2007): Australasian Biomechanics Conference, Auckland New Zealand, “The Pore Pressure and Structural Response of Intact and Degenerate Articular Cartilage During Unconfined Consolidation”.

  5. Fick JM (2004): The Hulbert Conference, Buffalo, New York, USA, “The Effect of Surface Treatments on the Burst Rate of Drug-Delivery Contact Lenses”.

  1. Book: Fick J, “Customized Contact Lens Treatments for in-the-Eye Medication, Drug Delivery Through Contact Lenses”, VDM Verlag Dr Muller Publishing, Germany, May 2009.
Contact: +358 20 7872211 (Switch), email: bbc-l [at] lists.uef.fi