Research Group

Lasse Pekka Räsänen
Ph.D.

Patient-specific Cartilage/Knee joint modelling based on clinical MRI

Personal information

  • Phone: +358 44 - 320 - 3376 (remove the pyphens)
  • Room: Me/240
  • Email: lasse.rasanen [at] uef.fi (please fix the address before mailing!) lasse.p.rasanen [at] gmail.com (please fix the address before mailing!)

  • Date of birth: 9 February 1987

  • Current research interests:
    • MRI data and image analysis
    • Implementation of cartilage architecture from clinical MRI into 3D finite elment model of knee joint
    • Patient-specific evaluation of knee joint mechanics
    • Clinical applications of MRI

  • Education:
    • Doctor of Philosophy, Medical Physics & Technology, University of Eastern Finland, 2016
    • Master of Science, Medical Physics, University of Eastern Finland, 2012
    • Bachelor of Science, Medical Physics, University of Eastern Finland, 2011
    • Graduate of Finnish Upper Secondary School, Mikkelin Lyseon lukio, 2006

  • Language proficiency:
    • Finnish, native language
    • English, fluent
    • Swedish, good
    • German, good

  • Skills:
    • MRI data analysis and image processing
    • ABAQUS FE modelling
    • Matlab
    • CAD, Photoshop, LaTex

  • Awards:
    • David Winter's Award for Young Investigator -finalist, Best oral presentation, International Society of Biomechanics, Glasgow, UK, July 2015.
    • Best Oral Presentation award from the Finnish Society of Medical Physics & Engineering, Otaniemi, Finland, February 2016.
    • Best Master's thesis award from the Finnish Society of Medical Physics & Engineering, Oulu, Finland, February 2013.

  • Reviews for Scientific Journals:
    • Osteoarthritis and Cartilage (Elsevier Ltd.)
    • Journal of Biomechanics (Elsevier Ltd.)
    • NMR in Biomedicine (John Wiley & Sons, Ltd.)
    • International Journal for Numerical Methods in Biomedical Engineering (John Wiley & Sons, Ltd.)

  • Hobbies:
      Football (...or soccer, depending on where you trod as an infant...), jogging/running, Gym.

Publications:

(full papers, conference proceedings)
  1. Rasanen LP, Tanska P, Zbyn S, van Donkelaar CC, Trattnig S, Nieminen MT and Korhonen RK. The effect of fixed charge density and cartilage swelling on mechanics of knee joint cartilage during simulated gait. J Biomech. 2017 Aug 16;61:34-44. doi: 10.1016/j.jbiomech.2017.06.041. Epub 2017

  2. Venalainen MS, Mononen ME, Salo J, Rasanen LP, Jurvelin JS, Toyras J, Viren T and Korhonen RK. Quantitative Evaluation of the Mechanical Risks Caused by Focal Cartilage Defects in the Knee. Sci Rep. 2016 Nov 29;6:37538. doi: 10.1038/srep37538.

  3. Rasanen LP, Tanska P, Mononen ME, Lammentausta E, Zbyn S, Venalainen MS, Szomolanyi P, van Donkelaar CC, Jurvelin JS, Trattnig S, Nieminen MT and Korhonen RK. Spatial variation of fixed charge density in knee joint cartilage from sodium MRI - Implication on knee joint mechanics under static loading. J Biomech. 2016 Oct 3;49(14):3387-3396. doi: 10.1016/j.jbiomech.2016.09.011. Epub

  4. Rasanen LP, Mononen ME, Lammentausta E, Nieminen MT, Jurvelin JS and Korhonen RK. Three dimensional patient-specific collagen architecture modulates cartilage responses in the knee joint during gait. Comput Methods Biomech Biomed Engin. 2016;19(11):1225-40. doi:

  5. Rasanen LP, Mononen ME, Nieminen MT, Lammentausta E, Jurvelin JS and Korhonen RK. Implementation of subject-specific collagen architecture of cartilage into a 2D computational model of a knee joint--data from the Osteoarthritis Initiative (OAI). J Orthop Res. 2013 Jan;31(1):10-22. doi: 10.1002/jor.22175. Epub 2012 Jul 5.

Under Review:

  1. Räsänen LP, Tanska P, Mononen ME, Lammentausta E, Zbyn S, Szomolanyi P, van Donkelaar CC, Jurvelin JS, Trattnig S, Nieminen MT, Korhonen RK. Subject-Specific spatial variation of Fixed Charge Density in Knee Joint Cartilage from 23Na-MRI – Implication on Knee Joint Mechanics under Static Loading.
  1. Venäläinen MS, Mononen ME, Salo J, Räsänen LP, Jurvelin JS, Töyräs J, Virén T, Korhonen RK. Computational Modeling Can Reveal Risk for the Progression of Focal Cartilage Defects in the Knee

Under Preparation:

  1. Räsänen LP, Tanska P, Lammentausta E, Zbyn S, van Donkelaar CC, Jurvelin JS, Trattnig S, Nieminen MT, Korhonen RK. The Effect of Fixed Charge Density and Cartilage Swelling on Knee Joint Mechanics During Gait.

Conference Proceedings:

  1. Podium Presentation: Räsänen LP, Tanska P, Zbyn S, Trattnig S, Nieminen MT, Korhonen RK. Effect of Cartilage Swelling and Fixed Charge Density on Knee Joint Mechanics During Gait. Transactions of the Orthopaedic Research Society, Orlando, FL, USA, 62:243, March 2016.
  2. Podium Presentation: Räsänen LP, Tanska P, Mononen ME, Szomolanyi P, Zbyn S, van Donkelaar CC, Trattnig S, Jurvelin JS, Nieminen MT, Korhonen RK. Implementation and Importance of the Subject-Specific Distribution of Fixed Charge Density of Articular Cartilage in the Knee. XXV Congress of the International Society of Biomechanics, Glasgow, UK, AS-0009, 2015.
  3. Räsänen LP, Zbyn S, Nieminen MT, Lammentausta E, Deligianni X, Bieri O, Trattnig S, Korhonen RK. Importance of Biexponential T2* and Partial Volume Effect Corrections on Quantification of Sodium Concentrations and Fixed Charge Density of Articular Cartilage with 23Na-MRI at 7T. Proc. Intl. Soc. Mag. Reson. Med (ISMRM) 23 (1897), Toronto, Ontario, Canada, 2015.
  4. Räsänen LP, Mononen ME, Nieminen MT, Lammentausta E, Jurvelin JS, Korhonen RK. Novel Submodeling Approach to Investigate Local Cartilage Responses in a Knee Joint - Importance of Patient-Specific Collagen Architecture. 7th World Congress on Biomechanics, Boston (MA, USA), July 6-11, 2014.
  5. Räsänen LP, Mononen ME, Nieminen MT, Lammentausta E, Jurvelin JS, Korhonen RK. Alternative Methods for Transforming T2 Anisotropy of MRI Into Collagen Architecture of Articular Cartilage – The Effect on Knee Joint Mechanics – Data From the Osteoarthritis Initiative (OAI). Proc. Intl. Soc. Mag. Reson. Med (ISMRM) 21 (3546), Salt Lake City, UT, USA, 2013.
  6. Räsänen LP, Mononen ME, Jurvelin JS, Korhonen RK. Importance of Patient-Specific Collagen Architecture on Knee Joint Stresses and Strains During Walking. Transactions of the Orthopaedic Research Society, 38:1678, San Antonio, Texas, 2013.
  7. Podium Presentation (Spotlight session): Räsänen LP, Mononen ME, Nieminen MT, Lammentausta E, Jurvelin JS, Korhonen RK. Implementation of Collagen Architecture from T2 Relaxation Time of MRI into a Biomechanical Model May Improve Estimation of Knee Joint Stresses. Transactions of the Orthopaedic Research Society, 36:68, Long Beach California, 2011.

Acknowledged in:

  1. Zbyn S, Mlynarik V, Juras V, Szomolanyi P, Trattnig S. Evaluation of cartilage repair and osteoarthritis with sodium MRI. NMR Biomed. 2015, DOI: 10.1002/nbm.3280
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