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Mikael Juhani Turunen
Ph.D.


University researcher

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Personal information

  • Phone:
    Work: +358 50 5777355
    Personal: +358 44 3447499
  • Room: Me/340
  • Email: mikael.turunen [at] uef.fi (please fix the address before mailing!)

  • Date of birth: 10 August 1984

  • Current position: University researcher, UEF

  • Current research interests: Bone fracture mechanisms and fracture criterion in nano- and microscale in healthy and osteoporotic bone. Osteoarthritis is subchondral bone and cross-talk with articular cartilage.

  • Previous research experience:
    • Post doctoral fellow (Academy of Finland) UEF, Sep 2015 - Aug 2018
    • Visiting Post doctoral fellow, Department of Biomedical Engineering, Lund University, Apr-Oct 2017
    • Post doctoral researcher, Department of Applied Physics, UEF, Oct 2013 - Aug 2015
    • Post doctoral researcher, Department of Biomedical Engineering, Lund University, Feb-May 2015
    • Doctoral student, Department of Applied Physics, UEF, Aug 2010 - Sep 2013
    • Part-time research assistant, Department of Applied Physics, University of Kuopio, Jun 2009 - Jun 2010

  • Education:
    • Title of Docent, Medical Physics, University of Eastern Finland, 2018
    • Ph.D., Medical Physics, University of Eastern Finland, 2013
    • M.Sc., Medical Physics, University of Eastern Finland, 2010
    • B.Sc., Medical Physics, University of Eastern Finland, 2010

  • Doctoral dissertation:
    Spectroscopic Characterization of Bone Composition - Alterations during Bone Formation, Maturation and Aging

  • Language proficiency:
    • Finnish, native language
    • English, fluent
    • Swedish, fair
    • German, fair

  • Membership in professional organizations:
    • European Society of Radiology (ESR)
    • European Society of Biomechanics (ESB)
    • Finnish Bone Society (FBS)
    • Finnish Physical Society (FPS)
    • Finnish Society of Medical Physics and Medical Engineering (LFTY)
    • Finnish Synchrotron Radiation User Organization (FSRUO)
    • National Doctoral Programme of Musculoskeletal Disorders and Biomaterials (TBDP)
    • Orthopaedic Research Society (ORS)
    • Radiological Society of Finland (SRY)

  • Significant funding & awards:
    • Finnish Academy Post doctoral fellow, 2015-2018
    • ESB Travel Award, 2013

  • Reviews for Scientific Journals:
    • Acta Biomaterialia
    • Aging and Disease
    • Applied Sciences
    • Biomechanics and Modeling in Mechanobiology
    • BioMed Research International
    • Bone
    • Clinical Interventions in Aging
    • Frontiers in Physics
    • IBMS BoneKEy
    • Journal of Biomedical Optics
    • Journal of Biological Physics
    • Journal of Clinical Medicine
    • Journal of Orthopaedic Research
    • Journal of Structural Biology
    • Materials
    • Symmetry

Publications: (h-index: 14, Citations)

Full papers listed in PubMed

    Full papers not listed in PubMed

  1. Huttunen JMJ, Turunen MJ, Honkanen JTJ, Töyräs J and Jurvelin JS. Estimation of systematic and spatially correlated components of random signals from repeated measurements: Application to contrast enhanced CT measurements. SIAM J Sci Comput. 2016 Jan;38(1):B77-B99. doi: 10.1137/15M1017727

  2. Singh SP, Parviainen I, Dekker H, Schulten EAJM, ten Bruggenkate CM, Bravenboer N, Mikkonen JJ, Turunen MJ, Koistinen AP and Kullaa AM. Raman microspectroscopy demonstrates alterations in human mandibular bone after radiotherapy. J Anal Bioanal Tech. 2015 Sep;6(6):276. doi: 10.4172/2155-9872.1000276

Conference proceedings

  1. Podium presentation: Bhattarai A, Mäkelä JTA, Pouran B, Weinans H, Kröger H, Grinstaff MW, Töyräs J and Turunen MJ. Effects of human articular cartilage constituents on simultaneous diffusion of cationic and non-ionic contrast agents. Physics Days 2020, Kuopio, Finland, 2020.

  2. Linus A, Ebrahimi E, Korhonen RK and Turunen MJ. Application of novel high-resolution spectroscopic method for characterization of the carilage cell environment. Physics Days 2020, Kuopio, Finland, 2020

  3. Das Gupta S, Finnilä M, Rieppo L, Kestilä I, Lutz-Bueno V, Turunen MJ, Folkeson E, Holler M, Neserin A, Hughes V, Guizar-Sicairos M, Isaksson H, Tjörnstrand J, Önnerfjord P, Englund M and Saarakkala S. The influence of osteoarthritic degeneration on the mineral composition and structural properties of human calcified cartilage and subchondral bone plate. 2020 World Congress of Osteoarthritis, Vienna, Austria, 2020.

  4. Turunen MJ, Bhattarai A, Grinstaff MW, Töyräs J and Mäkelä JTA. Effect of human articular cartilage constituents on simultaneous diffusion of cationic and non-ionic contrast agents. Annual meeting of the Orthopaedic Research Society, Phoenix, AZ, 2020.

  5. Podium presentation: Linus A, Ebrahimi M, Tanska P, Finnilä MA, Koistinen AP, Joukainen A, Kröger H, Saarakkala S, Turunen MJ and Korhonen RK. Characterization of Collagen Content in Chondrocyte Environment of Healthy and Osteoarthritic Human Tibial Cartilage. Annual meeting of the Orthopaedic Research Society, Phoenix, AZ, 2020.

  6. Podium presentation: Silva Barreto I, Le Cann S, Liebi M, Sotiriou V, Turunen MJ, Grünewald TA, Nowlan N and Isaksson H. Does Lack of Muscle Lead to Abnormal Crystal Growth During Murine Long Bone Development? Annual meeting of the Orthopaedic Research Society, Phoenix, AZ, 2020.

  7. Tong X, Burton IS, Turunen MJ, Koistinen AP, Isaksson H, Keronen S, Martola L, Honkanen E and Kröger H. Bone composition changes in patients with chronic kidney disease. American Society for Bone and Mineral Research 2019 Annual Meeting, Orlando, Florida, 2019.

  8. Turunen MJ, te Moller NCR, Nippolainen E, Mohammadi A, Mäkelä JTA, Afara IO, Koistinen AP, Brommer H and van Weeren PR. Compositional changes in subchondral bone and calcified cartilage in an equine cartilage defect model - A pilot study. ECSBM 2019, Dublin, Ireland, 2019.

  9. Finnilä MA, Turunen MJ, Kestilä I, Folkesson E, Neserin A, Hughes V, Isaksson H, Tjörnstrand J, Önnerfjord P, Saarakkala S and Englund M. Mineral crystal thickness in calcified cartilage and subchondral bone in human end-stage knee osteoarthritis and controls. 2019 World Congress of Osteoarthritis, Toronto, Canada, 2019.

  10. Podium presentation: Turunen MJ, Le Cann S, Tudisco E, Lovric G, Patera A, Hall SA and Isaksson H. Strain evolution and fracture criteria at sub-trabecular level in human trabecular bone under compression. Annual meeting of the Orthopaedic Research Society, Austin, TX, 2019.

  11. Podium presentation: Honkanen MKM, Saukko AEA, Turunen MJ, Shaikh R, Prakash M, Lovric G, Mäkelä JTA, Grinstaff MW and Töyräs J. Synchrotron uCT Reveals the Potential of the Dual-Contrast Technique for Quantitative Assessment of Human Articular Cartilage Composition. Annual meeting of the Orthopaedic Research Society, Austin, TX, 2019.

  12. Le Cann S, Silva Barreto I, Urga A, Sotiriou V, Levillain A, Turunen MJ, Liebi M, Bodey AJ, Johanssen U, Nowlan NC and Isaksson H. Multi-scale and multi-modal investigation of the onset of mineralization in embryonic mouse long bone. Annual meeting of the Orthopaedic Research Society, Austin, TX, 2019.

  13. Turunen MJ, Le Cann S, Tudisco E, Lovric G, Hall SA and Isaksson H. Repetitive Synchrotron X-ray Radiation May Alter Bone Collagen and Mineral. Annual meeting of the Orthopaedic Research Society, New Orleans, LA, 2018.

  14. Podium presentation: Gustafsson A, Mathavan N, Turunen MJ, Khayyeri H, Hall S and Isaksson H. Linking bone damage to microsctuctural and multiscale deformation using in situ loading with SAXS/WAXS. ESB Annual Congress, Seville, Spain, 2017.

  15. Podium presentation: Le Cann S, Tudisco E, Perdikouri C, Belfrage O, Turunen MJ, Kaestner A, Hall S, Tägil M and Isaksson H. Neutron tomography and in situ mechanical testing to characterize the bome-implant interface. 3rd International Conference on tomography on materials and Structures, Lund, Sweden, 2017.

  16. Turunen MJ, Khayyeri H, Guizar-Sicairos M, Aspenberg P and Isaksson H. Effects of Sample Preparation and Dehydration on Tendon Collagen Nanostructure. Annual meeting of the Orthopaedic Research Society, San Diego, CA, 2017.

  17. Isaksson H, Tudisco E, Perdikouri C, Le Cann S, Turunen MJ, Kaestner A, Tägil M and Hall S. Neutron tomographic imaging of bone-implant ingrowth. Annual meeting of the Orthopaedic Research Society, San Diego, CA, 2017.

  18. Tanska P, Ojanen X, Väänänen SP, Malo MKH, Turunen MJ, Töyräs J, Isaksson H, Korhonen RK and Jurvelin JS. Viscoelastic Contribution of Calcified and Collagen Matrices in Trabecular Bone in Nanoindentation. Annual meeting of the Orthopaedic Research Society, San Diego, CA, 2017.

  19. Podium presentation: Khayyeri H, Sepanloo P, Hammerman M, Turunen MJ, Aspenberg P and Isaksson H. Link between composition and mechanical behavior in immobilized healthy achilles tendons. ESB Annual Congress, Lyon, France, 2016.

  20. Podium presentation: Le Cann S, Tudisco E, Turunen MJ, Belfrage O, Hall S, Tägil M and Isaksson H. Tomographic X-ray imaging of bone-implant ingrowth with in situ mechanical testing. ESB Annual Congress, Lyon, France, 2016.

  21. Turunen MJ, Kaspersen JD, Bech M, Schaff F, Tägil M, Olsson U, Jurvelin JS and Isaksson H. Bone mineral crystal size and organization vary across rat bone cortex. Annual meeting of the Orthopaedic Research Society, Orlando, FL, 2016.

  22. Turunen MJ, Töyräs J, Kokkonen H and Jurvelin JS. Mineral density of subchondral bone may be quantitatively evaluated using a clinical cone beam computed tomography scanner. Annual meeting of the Orthopaedic Research Society, Las Vegas, NV, 2015.

  23. Honkanen JTJ, Turunen MJ, Tiitu V, Jurvelin JS and Töyräs J. Diffusion rate and equilibrium partition of an anionic contrast agent are different in cartilage and meniscus. Annual meeting of the Orthopaedic Research Society, Las Vegas, NV, 2015.

  24. Mathavan N, Turunen MJ, Bech M, Schaff F, Olsson U, Tägil M and Isaksson H. Characterization of composition and structure of callus tissue in fractures treated with BMP-7 and Zoledronate in an osteoporotic rat model. Annual meeting of the Orthopaedic Research Society, Las Vegas, NV, 2015.

  25. Turunen MJ, Jurvelin JS and Korhonen RK. Automated determination of zone thicknesses of articular cartilage based on chondrocyte shapes. World Congress of Biomechanics 2014.

  26. Mathavan N, Turunen MJ, Tägil M and Isaksson H. Investigating new characteristics of bone quality in the ovariectomized rat model of osteoporosis. World Congress of Biomechanics 2014.

  27. Mathavan N, Turunen MJ, Tägil M and Isaksson H. Elucidating the influence of ovariectomy-induced osteoporosis on the efficacy of fracture healing treatments in rats. Annual meeting of the Orthopaedic Research Society, New Orleans, LA, 2014.

  28. Podium presentation: Turunen MJ, Lages S, Labrador A, Olsson U, Tägil M, Jurvelin JS and Isaksson H. Composition and mineral structure of callus tissue during fracture healing. ESB Annual Congress, Patras, Greece, 2013.

  29. Podium presentation: Malo MKH, Riekkinen O, Turunen MJ, Isaksson H, Karjalainen JP, Töyräs J, and Jurvelin JS. In Situ Ultrasound Backscatter Measurements at Trochanter Major. ESUCB2013, Granada, Spain, 2013.

  30. Podium presentation: Turunen MJ, Prantner V, Jurvelin JS, Kröger H and Isaksson H. Composition and structure of human trabecular bone in different anatomical locations. ESB Annual Congress, Lisbon, Portugal, 2012.

  31. Podium presentation: Turunen MJ, Jurvelin JS, Kröger H and Isaksson H. Composition of human trabecular bone changes with age and differs between anatomical locations; evaluation with FTIR. Annual meeting of the Orthopaedic Research Society, San Fransisco, CA, 2012.

  32. Podium presentation: Turunen MJ, Bosemark P, Tägil M and Isaksson H. Local molecular composition in callus tissue of rats during bone healing: assessed by IR-spectroscopy. Baltic Bone and Cartilage Conference, Malmö, Sweden, 2011.

  33. Turunen MJ, Saarakkala S, Helminen HJ, Jurvelin JS and Isaksson H. Age-related changes in the composition and organization of the organic matrix in rabbit cortical bone. Annual meeting of the Orthopaedic Research Society, Long Beach, CA, 2011.

  34. Podium presentation: Kobrina Y, Turunen MJ, Saarakkala S, Jurvelin JS, Hauta-Kasari M and Isaksson H. Cluster analysis of infrared spectra of rabbit cortical bone samples during maturation and growth. The 6th International SPEC conference, Manchester, Great-Britain, 2010.

  35. Tamminen I, Mäyränpää M, Turunen MJ, Isaksson H, Mäkitie O, Jurvelin JS and Kröger H. Altered bone composition in fracture prone children with vertebral fracture. Annual meeting of the American Society for Bone and Mineral Research, Toronto, Canada, 2010.

  36. Turunen MJ, Saarakkala S, Rieppo L, Helminen HJ, Jurvelin JS and Isaksson H. Changes in rabbit bone composition during maturation - A comparison between Infrared and Raman microspectroscopy. Annual meeting of the Orthopaedic Research Society, New Orleans, LA, 2010.

  37. Podium presentation: Isaksson H, Turunen M, Rieppo L, Saarakkala S, Rieppo J, Kröger H and Jurvelin JS. Spectroscopic characterization of altered bone composition following osteoporosis or renal osteodystrophy. Annual meeting of the Orthopaedic Research Society, Las Vegas, NV, 2009.

  38. Töyras J, Turunen M, Lammi M, Jurvelin JS and Korhonen RK. Hyperosmolaric Contrast Agents in Cartilage Tomography May Expose Cartilage to Overload-Induced Cell Death. Annual meeting of the Orthopaedic Research Society, Las Vegas, NV, 2009.

Under review:

  1. Williams J, Huesa C, Turunen MJ, James AOo, Radzins O, Gardner W, Winfmill JF, Isaksson H, Tanner E, Riddell JS and Coupaud S. Time course changes to structural, mechanical and material properties of bone in young rats after spinal cord injury.

  2. Palander A, Dekker H, Hyvärinen M, Schulten EAJM, ten Bruggenkate CM, Koistinen A, Kullaa A and Turunen MJ. FTIR spectral characteristics of mandibular bone affected by cancer and radiation therapy.

  3. Bhattarai A, Mäkelä JTA, Behdad P, Weinans H, Kröger H, Grinstaff MW, Töyräs J and Turunen MJ. Effects of human articular cartilage constituents on simultaneous diffusion of cationic and non-ionic contrast agents.

  4. Khayyeri H, Hammerman M, Turunen MJ, Blomgran P, Notermans T, Guizar-Sicairos M, Eliasson P, Aspenberg P and Isaksson H. Diminishing effects of mechanical loading over time during rat Achilles tendon healing.

  5. Ebrahimi M, Turunen MJ, Finnilä MA, Joukainen A, Kröger H, Saarakkala S, Korhonen RK and Tanska P. Structure-function relationships in healthy and osteoarthritic human tibial cartilage.

  6. Silva Barreto I, Le Cann S, Ahmed S and Sotiriou V, Turunen MJ, Johansson U, Rodriguez Fernandez A, Grünewald TA, Liebi M, Nowlan N, Isaksson H. Multi-scale characterization of embryonic long bone mineralization in mice.

  7. Nykänen O, Leskinen H, Finnilä M, Karhula S, Turunen MJ, Töyräs J, Saarakkala S and Nissi MJ. The bright ultra-short echo time MRI signal seen at the osteochondral jusction is not located in the calcified cartilage.

  8. Turunen MJ, Le Cann S, Tudisco E, Goran L, Patera A, Hall SA and Isaksson H. Sub-trabecular strain evolution in human trabecular bone.

Contact: +358 29 4451111 (Switch), email: bbc-l [at] lists.uef.fi