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Mikko Samuli Venäläinen

Junior Researcher

Finite element modeling of knee joint function

Personal information

  • Phone: +358 40 7458193
  • Room: Me/331
  • Email: mikko.s.venalainen[at] (please fix the address before mailing!)

  • Date of birth: 18 May 1989

  • Current research interests: Finite element modeling of knee joint function

  • Education:
    • Master of Science, Medical Physics, University of Eastern Finland, 2014
    • Bachelor of Science, Applied and Computational Physics, University of Eastern Finland, 2012
    • Graduate of Finnish Upper Secondary School, Kallaveden lukio, 2008

  • Language proficiency:
    • Finnish, native language
    • English, good
    • Swedish, fair

  • Skills: Matlab, basics of C++ and Fortran

  • Hobbies: Music


(full papers, conference proceedings)
  1. Venalainen MS, Klen R, Mahmoudian M, Raitakan OT and Elo LL. Easy-to-use tool for evaluating the elevated acute kidney injury risk against reduced cardiovascular disease risk during intensive blood pressure control. J Hypertens. 2020 Jan 20. doi: 10.1097/HJH.0000000000002282.

  2. Mehmood A, Laiho A, Venalainen MS, McGlinchey AJ, Wang N and Elo LL. Systematic evaluation of differential splicing tools for RNA-seq studies. Brief Bioinform. 2019 Dec 5. pii: 5648232. doi: 10.1093/bib/bbz126.

  3. Vaananen SP, Grassi L, Venalainen MS, Matikka H, Zheng Y, Jurvelin JS and Isaksson H. Automated segmentation of cortical and trabecular bone to generate finite element models for femoral bone mechanics. Med Eng Phys. 2019 Aug;70:19-28. doi: 10.1016/j.medengphy.2019.06.015. Epub 2019

  4. Venalainen MS, Mononen ME, Salo J, Rasanen LP, Jurvelin JS, Toyras J, Viren T and Korhonen RK. Publisher Correction: Quantitative Evaluation of the Mechanical Risks Caused by Focal Cartilage Defects in the Knee. Sci Rep. 2019 Apr 4;9(1):5660. doi: 10.1038/s41598-019-41384-x.

  5. Myller KAH, ORCID: 0000-0001-8820-1322, Korhonen RK, Toyras J, Salo J, Jurvelin JS and Venalainen MS. Computational evaluation of altered biomechanics related to articular cartilage lesions observed in vivo. J Orthop Res. 2019 May;37(5):1042-1051. doi: 10.1002/jor.24273. Epub 2019 Mar 28.

  6. Eskelinen ASA, Mononen ME, Venalainen MS, Korhonen RK and Tanska P. Maximum shear strain-based algorithm can predict proteoglycan loss in damaged articular cartilage. Biomech Model Mechanobiol. 2019 Jun;18(3):753-778. doi:

  7. Bhosale SD, Moulder R, ORCID: 0000-0003-4742-0566, Venalainen MS, ORCID: 0000-0003-1777-4259, Koskinen JS, ORCID: 0000-0002-5920-9728, Pitkanen N, Juonala MT, Kahonen MAP, Lehtimaki TJ, Viikari JSA, Elo LL, Goodlett DR, Lahesmaa R and Raitakari OT. Serum Proteomic Profiling to Identify Biomarkers of Premature Carotid Atherosclerosis. Sci Rep. 2018 Jun 15;8(1):9209. doi: 10.1038/s41598-018-27265-9.

  8. Knuuttila M, Mehmood A, Maki-Jouppila J, Ryberg H, Taimen P, Knaapila J, Ettala O, Bostrom PJ, Ohlsson C, Venalainen MS, Laiho A, Elo LL, Sipila P, Makela SI and Poutanen M. Intratumoral androgen levels are linked to TMPRSS2-ERG fusion in prostate cancer. Endocr Relat Cancer. 2018 Sep;25(9):807-819. doi: 10.1530/ERC-18-0148. Epub 2018

  9. Halonen KS, Dzialo CM, Mannisi M, Venalainen MS, de Zee M and Andersen MS. Workflow assessing the effect of gait alterations on stresses in the medial tibial cartilage - combined musculoskeletal modelling and finite element analysis. Sci Rep. 2017 Dec 12;7(1):17396. doi: 10.1038/s41598-017-17228-x.

  10. Nuotio J, Pitkanen N, Magnussen CG, Buscot MJ, Venalainen MS, Elo LL, Jokinen E, Laitinen T, Taittonen L, Hutri-Kahonen N, Lyytikainen LP, Lehtimaki T, Viikari JS, Juonala M and Raitakari OT. Prediction of Adult Dyslipidemia Using Genetic and Childhood Clinical Risk Factors: The Cardiovascular Risk in Young Finns Study. Circ Cardiovasc Genet. 2017 Jun;10(3). pii: CIRCGENETICS.116.001604. doi:

  11. Venalainen MS, Mononen ME, Salo J, Rasanen LP, Jurvelin JS, Toyras J, Viren T and Korhonen RK. Quantitative Evaluation of the Mechanical Risks Caused by Focal Cartilage Defects in the Knee. Sci Rep. 2016 Nov 29;6:37538. doi: 10.1038/srep37538.

  12. Rasanen LP, Tanska P, Mononen ME, Lammentausta E, Zbyn S, Venalainen MS, Szomolanyi P, van Donkelaar CC, Jurvelin JS, Trattnig S, Nieminen MT and Korhonen RK. Spatial variation of fixed charge density in knee joint cartilage from sodium MRI - Implication on knee joint mechanics under static loading. J Biomech. 2016 Oct 3;49(14):3387-3396. doi: 10.1016/j.jbiomech.2016.09.011. Epub

  13. Venalainen MS, Mononen ME, Vaananen SP, Jurvelin JS, Toyras J, Viren T and Korhonen RK. Effect of bone inhomogeneity on tibiofemoral contact mechanics during physiological loading. J Biomech. 2016 May 3;49(7):1111-1120. doi: 10.1016/j.jbiomech.2016.02.033. Epub

  14. Hirvasniemi J, Thevenot J, Kokkonen HT, Finnila MA, Venalainen MS, Jamsa T, Korhonen RK, Toyras J and Saarakkala S. Correlation of Subchondral Bone Density and Structure from Plain Radiographs with Micro Computed Tomography Ex Vivo. Ann Biomed Eng. 2016 May;44(5):1698-709. doi: 10.1007/s10439-015-1452-y. Epub

  15. Venalainen MS, Mononen ME, Jurvelin JS, Toyras J, Viren T and Korhonen RK. Importance of material properties and porosity of bone on mechanical response of articular cartilage in human knee joint--a two-dimensional finite element study. J Biomech Eng. 2014 Dec;136(12):121005. doi: 10.1115/1.4028801.

  1. Venäläinen MS, Mononen, ME, Jurvelin, JS, Töyräs J, Virén, T, Korhonen RK, Importance of Bone Properties and Porosity on the Mechanical Response of Articular Cartilage in a Knee Joint. Transactions of the Orthopaedic Research Society, New Orleans, 2014.

Under review:

Acknowledged technical contributions:

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