Personal information

• Phone: +358 50 4635438
• Room: Me/240
• Email: petri.tanska [at] uef.fi (please fix the address before mailing!)

• Date of birth: 21 June 1987

• Current position: Post doctoral fellow, University of Eastern Finland, September 2016 - Present

• Previous position: Junior researcher, University of Eastern Finland, May 2012 - August 2016

• Current research interests:
  • Finite-element modeling and characterization of knee joint tissues (cartilage, meniscus, ligaments) and chondrocyte mechanics
  • Development of adaptive (degeneration/regeneration) and mechanobiological models for articular cartilage (and bone)
  • Implementation of imaging data into computational models
  • Constitutive material models of knee joint tissues
  • Optimization
  • Biomechanics of knee and knee osteoarthritis

• Education:
  • Doctor of Philosophy, Applied Physics, University of Eastern Finland, August 2016, (see PDF)
  • Master of Science, Applied physics (Medical Physics), University of Eastern Finland, April 2012, (see PDF)
  • Bachelor of Science, Physics, University of Eastern Finland, May 2011
  • Graduate of Finnish Upper Secondary School, Kuusaan lukio, June 2006

• Language proficiency:
  • Finnish, native language
  • English, fluent
  • German, fair
  • Swedish, fair

• Membership in professional organizations:
  • Member, Finnish Society of Medical Physics and Medical Engineering
  • Member, Orthopaedic Research Society
  • Member, European Society of Biomechanics

• Significant funding and awards:
  • European Society of Biomechanics (ESB) Best Doctoral Thesis in Biomechanics award (2nd place), 2017
  • Alfred Kordelin Foundation, 2015
  • Orthopaedic Research Society, 2015/2016 Collaborative Exchange Grant Award, 2015
  • Finnish Cultural Foundation, North-Savo regional fund, 2014

• Reviews for Scientific Journals:
  • Biomechanics and Modeling in Mechanobiology
  • Computers in Biology and Medicine
  • International Journal for Numerical Methods in Biomedical Engineering
  • Journal of Biomechanics
  • PeerJ
  • PLoS ONE
  • Osteoarthrithis and Cartilage

• Published research/technical reports:
  • Tanska P. Linking ABAQUS 2017 and Intel Parallel Studio XE2016 (Visual Fortran) in Windows 10 x64. ResearchGate. doi: 10.13140/RG.2.2.14625.40806

• Acknowledged technical contributions:
  • Muhonen V, Salonius E, Haaparanta AM, et al. (2016). Articular cartilage repair with recombinant human type II collagen/polylactide scaffold in a preliminary porcine study. Journal of Orthopaedic Research.
  • Mäkelä JT and Korhonen RK (2016). Highly nonlinear stress-relaxation response of articular cartilage in indentation: Importance of collagen nonlinearity. Journal of Biomechanics.
  • Honkanen JT, Danso EK, Suomalainen JS, et al. (2015). Contrast enhanced imaging of human meniscus using cone beam CT. Osteoarthrithis and Cartilage.

• Skills:
  • Constitutive material models, finite-element modeling, biomechanical testing, light microscopy, infrared microspectroscopy, image analysis, optimization, data-analysis & statistics
  • Programming & software: Abaqus, Isight, Comsol, Matlab, Java, HTML, FORTRAN, Python, C++, MS Office/Open Office, LaTeX, Windows and Unix environments

• Hobbies: Gym, bicycling, music and guitars

Publications: (h-index = 6, Citations)

1. Orozco GA, Tanska P, Florea C, Grodzinsky AJ and Korhonen RK. A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage. Sci Rep. 2018 Oct 22;8(1):15599. doi: 10.1038/s41598-018-33759-3.
   
   
2. Orozco GA, Tanska P, Mononen ME, Halonen KS and Korhonen RK. The effect of constitutive representations and structural constituents of ligaments on knee joint mechanics. Sci Rep. 2018 Feb 2;8(1):2323. doi: 10.1038/s41598-018-20739-w.
   
   
3. Tanska P, Julkunen P and Korhonen RK. A computational algorithm to simulate disorganization of collagen network in injured articular cartilage. Biomech Model Mechanobiol. 2018 Jun;17(3):689-699. doi: 10.1007/s10237-017-0986-3.
   
   
4. Mononen ME, Tanska P, Isaksson H and Korhonen RK. New algorithm for simulation of proteoglycan loss and collagen degeneration in the knee joint: Data from the osteoarthritis initiative. J Orthop Res. 2018 Jun;36(6):1673-1683. doi: 10.1002/jor.23811.
   
   
5. Ojanen X, Tanska P, Malo MKH, Isaksson H, Vaananen SP, Koistinen AP, Grassi L, Magnusson SP, Ribel-Madsen SM, Korhonen RK, Jurvelin JS and Toyras J. Tissue viscoelasticity is related to tissue composition but may not fully predict the apparent-level viscoelasticity in human trabecular bone - An experimental and finite element study. J Biomech. 2017 Dec 8;65:96-105. doi: 10.1016/j.jbiomech.2017.10.002.
   
   
6. Liukkonen MK, Mononen ME, Tanska P, Saarakkala S, Nieminen MT and Korhonen RK. Application of a semi-automatic cartilage segmentation method for biomechanical modeling of the knee joint. Comput Methods Biomech Biomed Engin. 2017 Oct;20(13):1453-1463. doi: 10.1080/10255842.2017.1375477.
   
   
7. Rasanen LP, Tanska P, Zbyn S, van Donkelaar CC, Trattnig S, Nieminen MT and Korhonen RK. The effect of fixed charge density and cartilage swelling on mechanics of knee joint cartilage during simulated gait. J Biomech. 2017 Aug 16;61:34-44. doi: 10.1016/j.jbiomech.2017.06.041.
   
   
8. Klets O, Mononen ME, Tanska P, Nieminen MT, Korhonen RK and Saarakkala S. Comparison of different material models of articular cartilage in 3D computational modeling of the knee: Data from the Osteoarthritis Initiative (OAI). J Biomech. 2016 Dec 8;49(16):3891-3900. doi: 10.1016/j.jbiomech.2016.10.025.
   
   
9. Rasanen LP, Tanska P, Mononen ME, Lammentausta E, Zbyn S, Venalainen MS, Szomolanyi P, van Donkelaar CC, Jurvelin JS, Trattnig S, Nieminen MT and Korhonen RK. Spatial variation of fixed charge density in knee joint cartilage from sodium MRI - Implication on knee joint mechanics under static loading. J Biomech. 2016 Oct 3;49(14):3387-3396. doi: 10.1016/j.jbiomech.2016.09.011.
   
   
10. Florea C, Tanska P, Mononen ME, Qu C, Lammi MJ, Laasanen MS and Korhonen RK. A combined experimental atomic force microscopy-based nanoindentation and computational modeling approach to unravel the key contributors to the time-dependent mechanical behavior of single cells. Biomech Model Mechanobiol. 2017 Feb;16(1):297-311. doi: 10.1007/s10237-016-0817-y.
    
    
11. Puhakka PH, Te Moller NC, Tanska P, Saarakkala S, Tiitu V, Korhonen RK, Brommer H, Viren T, Jurvelin JS and Toyras J. Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound. Acta Orthop. 2016 Aug;87(4):418-24. doi: 10.1080/17453674.2016.1180578.
    
    
12. Mononen ME, Tanska P, Isaksson H and Korhonen RK. A Novel Method to Simulate the Progression of Collagen Degeneration of Cartilage in the Knee: Data from the Osteoarthritis Initiative. Sci Rep. 2016 Feb 24;6:21415. doi: 10.1038/srep21415.
    
    
13. Korhonen RK, Tanska P, Kaartinen SM, Fick JM and Mononen ME. New Concept to Restore Normal Cell Responses in Osteoarthritic Knee Joint Cartilage. Exerc Sport Sci Rev. 2015 Jul;43(3):143-52. doi: 10.1249/JES.0000000000000051.
    
    
14. Tanska P, Mononen ME and Korhonen RK. A multi-scale finite element model for investigation of chondrocyte mechanics in normal and medial meniscectomy human knee joint during walking. J Biomech. 2015 Jun 1;48(8):1397-406. doi: 10.1016/j.jbiomech.2015.02.043.
    
    
15. Danso EK, Makela JT, Tanska P, Mononen ME, Honkanen JT, Jurvelin JS, Toyras J, Julkunen P and Korhonen RK. Characterization of site-specific biomechanical properties of human meniscus-Importance of collagen and fluid on mechanical nonlinearities. J Biomech. 2015 Jun 1;48(8):1499-507. doi: 10.1016/j.jbiomech.2015.01.048.
    
    
16. Tanska P, Turunen SM, Han SK, Julkunen P, Herzog W and Korhonen RK. Superficial collagen fibril modulus and pericellular fixed charge density modulate chondrocyte volumetric behaviour in early osteoarthritis. Comput Math Methods Med. 2013;2013:164146. doi: 10.1155/2013/164146.
    
    
17. Turunen SM, Lammi MJ, Saarakkala S, Han SK, Herzog W, Tanska P and Korhonen RK. The effect of collagen degradation on chondrocyte volume and morphology in bovine articular cartilage following a hypotonic challenge. Biomech Model Mechanobiol. 2013 Jun;12(3):417-29. doi: 10.1007/s10237-012-0409-4.
    
    

1. Tanska P, Ronkainen A, Fick JM, Reunamo A, Herzog W, Korhonen RK. The Ratio Between Extra- and Pericellular Matrix Proteoglycan Content and Applied Loading Magnitude Modulates Chondrocyte Volume Loss Following Partial Meniscectomy In the Knee - Experimental and Computational Analysis. Transactions of the Orthopaedic Research Society, New Orleans, LA, USA, 64:1338, 2018 (Poster presentation).


2. Orozco G, Tanska P, Eskelinen AS, Florea C, Grodzinsky A, Korhonen RK. Mechanisms to Reveal How Normal Dynamic Loading Causes Proteoglycan Loss in Mechanically Injured Cartilage: A Mechanobiological Model Combined With Experimental Findings. Transactions of the Orthopaedic Research Society, New Orleans, LA, USA, 64:1333, 2018 (Poster presentation).


3. Tanska P, Venäläinen MS, Erdemir A, Korhonen RK. Importance of Fiber Representation and Cell Distribution on Cell Deformation Behavior in Articular Cartilage. 23rd Congress of the European Society of Biomechancis, Seville, Spain, 2017 (Podium presentation).


4. Tanska P, Ojanen X, Väänänen SP, Malo MKH, Turunen MJ, Töyräs J, Isaksson H, Korhonen RK, Jurvelin JS. Viscoelastic Contribution of Calcified and Collagen Matrices in Trabecular Bone in Nanoindentation. Transactions of the Orthopaedic Research Society, San Diego, CA, USA, 63:1702, 2017 (Poster presentation).


5. Ronkainen A, Tanska P, Fick JM, Herzog W, Korhonen RK. Biomechanical Responses of Chondrocytes After Partial Meniscectomy - Importance of Cartilage Structure. Transactions of the Orthopaedic Research Society, San Diego, CA, USA, 63:471, 2017 (Poster presentation).


6. Eskelinen A, Tanska P, Mononen ME, Venäläinen MS, Korhonen RK. Shear Strain Can Trigger Proteoglycan Loss in Injured Cartilage. Transactions of the Orthopaedic Research Society, San Diego, CA, USA, 63:1434, 2017 (Poster presentation).


7. Orozco G, Tanska P, Mononen ME, Halonen KS, Korhonen RK. Importance of Compression-Tension Nonlinearity of Ligaments on Human Knee Joint Biomechanics. Transactions of the Orthopaedic Research Society, San Diego, CA, USA, 63:233, 2017 (Podium presentation).


8. Mononen ME, Tanska P, Isaksson H, Korhonen RK. New Mechanobiological Framework for Prediction of Simultaneous Proteoglycan Loss and Collagen Degeneration During Knee Osteoarthritis. Transactions of the Orthopaedic Research Society, San Diego, CA, USA, 63:263, 2017 (Podium presentation).


9. Tanska P, Julkunen P, Korhonen RK. The Effect of Strains and Stresses on Collagen Reorientation in Intact and Injured Cartilage. 14th International Symposium on Computer Menthods in Biomechanics and Biomedical Engineering, Tel Aviv, Israel, September 2016 (Podium presentation).


10. Mononen ME, Tanska P, Korhonen RK. Prediction of Subject Specific Cartilage Degeneration within the Knee and Comparison to Experiments: data from the Osteoarthritis Initiative. 14th International Symposium on Computer Menthods in Biomechanics and Biomedical Engineering, Tel Aviv, Israel, September 2016 (Podium presentation).


11. Räsänen LP, Tanska P, Zbyn S, Lammentausta E, Trattnig S, Jurvelin JS, Nieminen MT, Korhonen RK. The Effect of Cartilage Swelling and Fixed Charge Density on Knee Joint Mechanics During Gait. 9th International Workshop on Osteoarthritis Imaging, Oulu, Finland, June 2016 (Podium presentation).


12. Tanska P, Julkunen P, Korhonen RK. A Computational Algorithm to Simulate Collagen Reorientation in Injured Cartilage. 9th International Workshop on Osteoarthritis Imaging, Oulu, Finland, June 2016 (Poster presentation).


13. Liukkonen MK, Mononen ME, Tanska P, Saarakkala S, Nieminen M, Korhonen RK. New Semi-Automatic Segmentation Method for Biomechanical Orthopedic Applications. Transactions of the Orthopaedic Research Society, Orlando, FL, USA, 62:344, 2016 (Podium presentation).


14. Räsänen LP, Tanska P, Zbyn S, Trattnig S, Nieminen MT, Korhonen RK. The Effect of Cartilage Swelling and Fixed Charge Density on Knee Joint Mechanics During Gait. Transactions of the Orthopaedic Research Society, Orlando, FL, USA, 62:243, 2016 (Podium presentation).


15. Muhonen VM, Salonius E, Haaparanta A-M, Järvinen EA, Paatela T, Meller AS, Hannula M, Björkman M, Pyhältö, Tanska P, Aula A, Ellä V, Vasara A, Töyräs J, Kellomäki M, Kiviranta IK. ACI with recombinant human type II collagen / polylactide scaffold enhances articular cartilage repair in a porcine model. 12th World Congress of the International Cartilage Repair Society, Chicago, IL, USA, 2015 (Poster presentation).


16. Klets O, Mononen ME, Tanska P, Korhonen RK, Saarakkala S. Comparison of simplified and complex material models of articular cartilagein computational modeling of knee joint mechanics during gait: data from the Osteoarthritis Initiative (OAI). 13th International Symposium on Computer Menthods in Biomechanics and Biomedical Engineering, Montreal, Canada, 2015 (Podium presentation).


17. Räsänen LP, Tanska P, Mononen ME, Szomolanyi P, Zbyn S, van Donkelaar CC, Trattnig S, Jurvelin JS, Nieminen M, Korhonen RK. Implementation and Importance of the Subject-Specific Distribution of Fixed Charge Density of Articular Cartilage in the Knee. XXV Congress of the International Society of Biomechanics, Glasgow, United Kindom, AS-0009, 2015 (Podium presentation).


18. Mononen ME, Tanska P, Isaksson H, Korhonen RK. Prediction of Collagen Degeneration and Osteoarthritis in Knee Joints from Normal and Overweight Subjects – Adaptive Computational 3D Analysis. XXV Congress of the International Society of Biomechanics, Glasgow, United Kindom, AS-0503, 2015 (Podium presentation).


19. Tanska P, Mononen ME, and Korhonen RK. Chondrocyte Mechanics in Intact and Meniscectomy Human Knee Joints During Walking. Transactions of the Orthopaedic Research Society, Las Vegas, NV, USA, 61:249, 2015.


20. Danso EK, Mäkelä JTA, Tanska P, Mononen ME, Honkanen JTJ, Jurvelin JS, Töyräs J, Julkunen P, Korhonen RK. Site-Specific Biomechanical Properties of Human Meniscus – Importance of Collagen and Fluid Nonlinearities. Transactions of the Orthopaedic Research Society, Las Vegas, NV, USA, 61:249, 2015 (Podium presentation).


21. Tanska P, Mononen ME, and Korhonen RK. Biomechanical Responses of Chondrocyte in Healthy and Osteoarthritic Human Knee Joint - Effect of Overweight. 12th Intertational Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Amsterdam, The Netherlands, October 2014 (Podium presentation).


22. Tanska P, Mononen ME, and Korhonen RK. Deformation Behavior of Articular Chondrocytes in a Knee Joint - Multiscale Computational Analysis. 7th World Congress of Biomechanics, Boston, MA, USA, 2014 (Invited talk).


23. Tanska P, Mononen ME, and Korhonen RK. Medial Meniscectomy Causes Elevated Chondrocyte Fluid Pressure in Human Knee Joint During Walking. 7th World Congress of Biomechanics, Boston, MA, USA, 2014.


24. Tanska P, Julkunen P, and Korhonen RK. Reduced Superficial Proteoglycan Content Increases Collagen Fibril Strains Following Impact Loading. Transactions of the Orthopaedic Research Society, New Orleans, LA, USA, 60:1313, 2014.


25. Florea C, Mononen ME, Tanska P, Lammi MJ, Laasanen MS and Korhonen RK. Intracellular Fluid Flow Controls Viscoelastic Properties of Chondrocytes in Nanoindentation. Transactions of the Orthopaedic Research Society, New Orleans, LA, USA, 60:0434, 2014.


26. Mononen ME, Tanska P, and Korhonen RK. Deformation Behavior Of Superficial Cartilage Chondrocyte Within Intact And Meniscectomized Knee Joints During Walking - Effect Of Conservative Treatment. Transactions of the Orthopaedic Research Society, New Orleans, LA, USA, 60:0442, 2014.


27. Tanska P, Bidhendi AJ, Mononen M, and Korhonen RK. Importance of Split-Lines of Cartilage and Collagen Fibrils in the Pericellular Matrix on Cell Deformations in a Knee Joint. Proceedings of the 11th International Symposium, Computer Methods in Biomechanics and Biomedical Engineering, Salt Lake City, UT, USA, 2013 (Invited talk).


28. Tanska P, Julkunen P, Lammi MJ, and Korhonen RK. Tensile Strains May Be More Important Than Compressive Strains to Modulate Proteoglycan Synthesis in Dynamically Loaded Articular Cartilage. Transactions of the Orthopaedic Research Society, San Antonio, TX, USA, 38:0550, 2013.


29. Tanska P, Julkunen P, and Korhonen RK. Collagen Fibrils of Articular Cartilage Modulate Cell Deformations in Early Osteoarthritis. Transactions of the Orthopaedic Research Society, Long Beach, CA, USA, 36:2174, 2011.


30. Turunen SM, Lammi MJ, Saarakkala S, Han SK, Herzog W, Tanska P, and Korhonen RK. Hypotonic Challenge Alters Cell Volumes Differently in Enzymatically Treated and Intact Articular Cartilage. Transactions of the Orthopaedic Research Society, Long Beach, CA, USA, 36:2171, 2011.

Under review: