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Simo Pekka Ojanen
Ph.D. Student, M.Sc.


Junior Researcher / PhD candidate


Biomechanics of articular cartilage and chondrocytes

Personal information

  • Phone: +358 50 4399524
  • Room: Me/336
  • Email: simo.ojanen[at]uef.fi (please fix the address before mailing!)

  • Year of birth: 1989

  • Current research interests: Biomechanics of articular cartilage and chondrocytes, progression of osteoarthritis (OA), early post-traumatic osteoarthritis, anterior cruciate ligament transection (ACLT)

  • Education:
    • Master of Science, Applied Physics, University of Eastern Finland, August 2014
    • Bachelor of Science, Physics, University of Eastern Finland, June 2013
    • Graduate of Finnish Upper Secondary School, Joensuun Niinivaaran lukio, June 2008

  • Language proficiency:
    • Finnish, native language
    • English, fluent
    • Swedish, fair

  • Skills:
    • Digital densitometry
    • Confocal microscopy
    • Cartilage tissue and chondrocyte biomechanics
    • Image analysis
    • Polarized light microscopy
    • Fourier-transform infrared spectroscopy (FTIR)
    • Programming: Matlab, Python (basics), Abaqus (basics)

  • Hobbies: Floorball, gym and other sports, music

Publications:

(full papers, conference proceedings)
  1. Ojanen SP, Finnilä MAJ, Reunamo AE, Ronkainen AP, Herzog W, Saarakkala S, Korhonen RK, Site-specific Proteoglycan Content Is Better Maintained In The Pericellular Than Extracellular Matrix In Early Post-traumatic Osteoarthritis. 13th Science day of the Campus of Kontikangas - "Regulation of the Immune system - from bench to bedside", February 2016.

  2. Podium presentation: Ojanen SP, Finnilä MAJ, Reunamo AE, Ronkainen AP, Herzog W, Saarakkala S, Korhonen RK, Site-specific Proteoglycan Content Is Better Maintained In The Pericellular Than Extracellular Matrix In Early Post-traumatic Osteoarthritis. Osteoarthritis and Cartilage 24:S17-S18 · April 2016.

  3. Ojanen SP, Finnilä MAJ, Saarela K, Happonen E, Herzog W, Saarakkala S, Korhonen RK, Site-specific Changes In Deformation Of Articular Cartilage Chondrocytes At Very Early Stage Of Post-traumatic OA. Transactions of the Orthopaedic Research Society· San Diego, 2017.

  4. Casula V, Kajabi AW, Ojanen S, Finnilä M, Korhonen R, Herzog W, Saarakkala S, Nissi M, Nieminen MT, Multiparametric MRI assessment reveals early cartilage degeneration at 2 and 8 weeks after anterior cruciate ligament transection in a rabbit model. Proc. Intl. Soc. Magn. Reson. Med. 25 (5490), Honolulu, Hawaii, USA 2017.

  5. Podium presentation: Finnilä MAJ , Ojanen S, Saarakkala S, Hewitt C, Herzog W, Nieminen P, Hart DA, Korhonen RK, Increased cartilage remodelling and impaired chondrocyte mechanotransduction in early post-traumatic osteoarthritis. Osteoarthritis and Cartilage, 25:S67-S68, April 2017.

  6. Podium presentation: Ojanen SP, Finnilä MAJ, Mäkelä J, Saarela K, Happonen E, Herzog W, Saarakkala S, Korhonen RK, Site-specific Changes Of Articular Cartilage Biomechanics and Chondrocytes Deformation in Early OA. 23rd Congress of the European Society of Biomechanics, July 2.-5., 2017, Seville, Spain.

  7. Ojanen SP, Finnilä MAJ, Saarela K, Mäkelä J, Herzog W, Saarakkala S, Korhonen RK, ACLT of Rabbits Alters PG Content and Cartilage Biomechanics Two Weeks Post-surgery. 15th Science day of the Campus of Kontikangas, February 2018.

  8. Ojanen SP, Finnilä MAJ, Saarela K, Mäkelä J, Herzog W, Saarakkala S, Korhonen RK, ACL transection of rabbits alter FCD content, tissue modulus and cell deformation mostly in the lateral femoral condyle cartilage 2 weeks post-surgery. Transactions of the Orthopaedic Research Society, New Orleans, 2018.

  9. Ojanen SP, Finnilä MAJ, Saarela K, Herzog W, Saarakkala S, Korhonen RK, Time-dependent changes of FCD content during the progression of osteoarthritis in rabbits. Transactions of the Orthopaedic Research Society, New Orleans, 2018.

  10. Kajabi AW, Casula V, Ojanen S, Finnilä M, Korhonen R, Herzog W, Saarakkala S, Nissi MJ and Nieminen MT, T1ρ dispersion assessment of articular cartilage in a rabbit ACL transection model. Proc. Intl. Soc. Magn. Reson. Med 26, 2018.

Under review:

  1. Ojanen SP, Finnilä MAJ, Reunamo AE, Ronkainen AP, Mikkonen S, Herzog W, Saarakkala S, Korhonen RK, Site-specific glycosaminoglycan content is better maintained in the pericellular matrix than the extracellular matrix in early post-traumatic osteoarthritis.

Acknowledged in:

  1. Puhakka PH, te Moller NCR, Afara IO, Mäkelä JTA, Tiitu V, Korhonen RK, Brommer H, Virén T, Jurvelin JS, Töyräs J, Estimation of acticular cartilage properties using multivariate analysis of optical coherence tomography signal. Osteoarthritis and Cartilage, 2015.

  2. Puhakka PH, te Moller NCR, Tanska P, Saarakkala S, Tiitu V, Korhonen RK, Brommer H, Virén T, Jurvelin JS, Töyräs J, Optical coherence tomography enables accurate equine cartilage thickness measurement for determination of speed of sound. Acta Orthopaedica, 2016.

Contact: +358 29 4451111 (Switch), email: bbc-l [at] lists.uef.fi